Why inbreeding causes genetic disorders

The team was also just looking for the most extreme examples of inbreeding. Ultimately, this is another step for research efforts into the prevalence and lasting effects of inbreeding. New genetic resources are making this kind of research easier and more accessible — before the advent of genome sequencing and genetic databases, this study would have been impossible.

Register or Log In. The Magazine Shop. Login Register Stay Curious Subscribe. Charles II, the last of the Spanish Hapsburgs. Generations of inbreeding left him infertile, in addition to numerous additional health problems.

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Scientists recommend that a sire and dam should share no more than 6. Inbreeding also increases the risk of disorders caused by recessive genes. These disorders can lead to calf abnormalities, miscarriages and stillbirths.

Animals must have two copies of a recessive gene to have the disorder. They receive one copy of the gene from each parent. Animals that are closely related are more likely to carry a copy of the same recessive gene. This increases the risk they will both pass a copy of the gene onto their offspring. We have several tools available to prevent matings between animals that carry the same recessive gene.

Our DataMATE app makes it easy for our artificial breeding technicians to calculate the risk of a particular mating.

DataMATE issues a warning if the animals are likely to share more than 6. The technician can then inseminate the cow with a more suitable bull.